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[SA_scat] ITC 2013: SAXS and computational techniques tostudy intrinsically disordered proteins
- To: "Discussion list for the Small-Angle Scattering community" <sa_scat@iucr.org>
- Subject: [SA_scat] ITC 2013: SAXS and computational techniques tostudy intrinsically disordered proteins
- From: "Erica Valentini" <erica@embl-hamburg.de>
- Date: Wed, 09 Jan 2013 15:58:31 +0100
- In-Reply-To: <50EC3ADA.300@ibs.fr>
- References: <50EC3ADA.300@ibs.fr>
Dear Colleagues, We announce the Intensive Training Course 2013: SAXS and computational techniques to study intrinsically disordered proteins. EMBL, Hamburg, March 11-16, 2013 This Intensive Training Course is organized by a IDPbyNMR project (www.IDPbyNMR.eu), which is a Marie Curie activity funded under the European Commission FP7 people programme. The Course is dedicated to application of Small Angle X-ray Scattering and Computational Techniques to studying of intrinsically disordered proteins (IDPs). The course includes theoretical lectures, tutorials on SAXS data analysis and computational techniques and measurements at the EMBL high brilliance synchrotron BioSAXS beamline P12 (storage ring PETRA-3, DESY). The theoretical part covers basics SAXS, sample preparation for the measurement, initial data processing approaches, ab initio and rigid body modeling, analysis of polydisperse systems, application of ensemble optimization method for studying of flexible proteins and incorporation of SAXS in molecular dynamics simulations . The methods combining NMR and SAXS data for a conformational description of IDPs will be presented. The practical part includes tutorials of ATSAS package programs, Asteroids and Flexible-Meccano software, measurements at the SAXS beamline and analysis of obtained data. Participants may bring their own samples to perform measurements on the beamline during the course. Students should bring their own laptops for tutorials. Topics of the talks and tutorials: ? Introduction to SAXS ? Sample preparation and characterization ? Data reduction and processing ? Ab initio methods ? Rigid body refinement ? Mixture analysis ? Ensemble optimization method tutorial ? Asteroids software ? Flexible-Meccano method ? Incorporation of SAXS measurements as structural restraints in molecular dynamics simulations How to Apply This Intensive Training Course is open for up to 5 external students. The applicants should send an E-mail to erica@embl-hamburg.de with CC to mkachala@embl-hamburg.de and ?ITC 2013? as the subject indicating the following: ? Full name (name, last name) ? Birth date ? Nationality ? Affiliation ? Current position (PhD/post-doc) ? Brief abstract of applicants current research (max half of A4 size page) ? List of publications ? Letter of support by applicant?s supervisor. The registration fee of 100 EUR should be paid in cash on-site. Selected applicants will have to cover their travel expenses and accommodation (the meals are included in the fee). The application is open until 15th of February 2013. -- Erica Valentini EMBL-Hamburg Notkestrasse 85, +49 040 899 02 182 _______________________________________________ sa_scat mailing list sa_scat@iucr.org http://mailman.iucr.org/mailman/listinfo/sa_scat
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