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research position wanted

Dear colleagues:

I am posting my Curriculum Vitae to ask for your assistance. 
Since 1996 I have been living in the United States and looking
for opportunities for researching in the field of  structural 
analysis of biological macromolecules. 

I have over 20 years of experience in fundamental and applied 
researches for molecular biology and biomedicine by structural  
physical methods such as X-ray diffraction (X-ray crystallographic 
analysis and SAXS technique) and electron microscopy: 
1)Development of new method for analyzing SAXS data from 
the equilibrium enzyme-substrate  mixtures which allows one 
to determine equilibrium, stoichiometric and structural parameters
of macromolecular complexes formed; the following macromolecular
systems were studied: (a) Eco dam methyltransferase with synthetic
double-stranded oligonucleotide containing the enzyme recognition
specific site; (b) phenylalanyl-tRNA-synthetase from E. coli with
phenylalanyl-tRNA; (c) beef pancreas tryptophanyl-tRNA-synthetase
at physiological (20 - 45 degrees C) temperatures; 2)Development
of new method for express-diagnosis of human susceptibility to 
atherosclerosis based on analysis of SAXS data; determination of 
lipid core profiles of major plasma lipoproteins from various 
patients; 3)  Determination of three-dimensional structures of 
inorganic and organic crystals containing iodide by X-ray diffraction. 

I will be grateful if you consider my CV. I hope my research 
experience and  background find your interest. I look forward 
to receiving your assistance. Thank you.

Sincerely,

Vladimir Vavilin



VLADIMIR VAVILIN,  Ph.D.
108 Enchanted Hills Road, Apt. 104
Owings Mills, MD 21117 
Phone: 410-581-1023
E-mail: viv@erols.com 

OBJECTIVE  

Research position in structural biophysics or crystallography.

EDUCATION    

1972-1975  Institute of Crystallography AN USSR, Moscow, USSR
Ph. D. Degree in Crystallography. Dissertation: The Crystal Structures
of  Iodide Complexes of Potassium, 1976.  Adviser: Professor 
Nikolay V. Belov 

1967-1972  Gorky State University, Gorky, USSR
M. Sc. Degree in Physics ( specialization in X-ray Crystallography )

RESEARCH EXPERIENCE 

1993-1995  Associate Professor of Biophysics, Department of Biology, 
Nizhny Novgorod State University, Nizhny Novgorod, Russia

1986-1992  Head of Laboratory of X-ray Diffraction, Department of 
Biophysics, Institute of Molecular Biology, Novosibirsk, Russia

1981-1985  Leader of Research Project, Department of Biophysics,
Institute of Molecular Biology, Novosibirsk, Russia

1978-1981  Senior Researcher, Laboratory of Electron Microscopy
and X-ray Diffraction, Institute of Molecular Biology, Novosibirsk, 
Russia 

1976-1977  Junior Researcher, Laboratory of Electron Microscopy
and X-ray Diffraction, Institute of Molecular Biology, Novosibirsk,
Russia 

1975-1976  Postdoctoral Fellow, Laboratory of  Macromolecular 
Crystallography, Institute of Crystallography AN SSSR, Moscow, 
Russia 

1972-1975  Predoctoral Fellow, Laboratory of X-ray Crystallography,
Institute of Crystallography AN SSSR, Moscow, Russia 

HONORS

Diploma of Senior Researcher in Biophysics, 1986, Institute of 
Molecular Biology, Novosibirsk, Russia

PREDOCTORAL FELLOW SUPERVISION

1983-1991  Institute of Molecular Biology, Novosibirsk, Russia
Sergey  Zaitsev, Ph.D. (1983-1988), Yuriy  Gusev, Ph.D. (1984-1989),
Fedor  Tuzikov, Ph.D. (1983-1990), Vasiliy  Poryvaev, Ph.D. 
(1985-1990), Nikolay  Krivenchuk, Ph.D. (1986-1991)

TEACHING EXPERIENCE 

1993-1996  Lecturer, Introduction to Physics of Complex Biological 
Systems, Department of Biology, Nizhny Novgorod State University,
Nizhny Novgorod, Russia

PROFESSIONAL MEMBERSHIPS
                      
American Association for the Advancement of Science (AAAS)

SELECTED PUBLICATIONS

Vavilin, V.I., Gladkikh, E.A., Soldatov, E.A., Kuzmin, E.A., Iliukhin,
V.V., Belov, N.V. On crystalline structure of indium pyrogermanate,
In2 Ge2 O7, Dokl . Akad . Nauk SSSR , 213: 837-839, 1973.

Vavilin, V.I., Ionov, V.M., Iliukhin, V.V., Belov, N.V. Crystal structure
of rhombic mixed potassium iodate, KIO3 HIO3, Dokl. Akad. Nauk 
SSSR, 219: 1108-1110, 1974.

Vavilin, V.I., Iliukhin, V.V., Belov, N.V. Crystal structure of acid potassium 
bisulphate-iodate, Dokl. Akad. Nauk SSSR, 219: 1352-1354, 1974.

Vavilin, V.I., Ionov, V.M., Iliukhin, V.V., Belov, N.V. Crystal structure
of new monoclinic modification of acid K-iodate, KIO3 HIO3, Dokl. 
Akad. Nauk SSSR, 224: 1066-1068, 1975.

Vavilin, V.I., Burstein, I.F., Shchedrin, B.M., Iliukhin, V.V., Belov, N.V.
Deciphering of the crystal structure of primary potassium iodate,
Dokl. Akad. Nauk SSSR, 226: 1073-1075, 1976.

Vavilin, V.I., Iliukhin, V.V., Belov, N.V.  On the crystal structure of 
primary potassium iodate, KIO3 2HIO3, Dokl. Akad. Nauk SSSR,
226: 1319-1322, 1976.

Dianov, G.L., Mazin, A.V., Zaitsev, B.N., Vavilin, V.I., Salganik, R.I.
Directed modification of the early region of T7 bacteriophage DNA  
by alkylation in the R-loop formed by a modified transcript, Mol. Biol.
(USSR), 14: 261-264, 1980.

Tuzikov, F.V., Zinoviev, V.V., Yashina, L.N., Vavilin, V.I., Gorbunov, Yu.A., 
Popov, S.G., Degtyarev, S.Kh., Malygin, E.G., Sadovsky, A.P., Buryanov, Ya.I., 
Bayev, A.A.  Study of the substrate-induced changes in  the state of 
Eco dam methylase using a method of small-angle X-ray scattering, 
Mol. Biol. (USSR), 20: 1002-1007, 1986.

Tuzikov, F.V., Zinoviev, V.V., Vavilin, V.I., Malygin, E.G. Small-angle
X-ray scattering study of enzyme-substrate interaction in solution, 
Studia biophysica, 125: 169-172, 1988.
 
Tuzikov, F.V., Zinoviev, V.V., Vavilin, V.I., Maligin, E.G., Ankilova,
V.N., Moor, N.A., Lavrik, O.I.  Application of the small-angle X-ray
scattering technique for the study of equilibrium enzyme-substrate 
interactions of phenylalanyl-tRNA synthetase from E. coli with 
phenylalanyl-tRNA, FEBS Letters, 232: 107-110, 1988.

Tuzikov, F.V., Zinoviev, V.V., Vavilin, V.I., Malygin, E.G., Ankilova, V.N., 
Moor, N.A., Lavrik, O.I. Study of the complex-formation of 
phenylalanyl-tRNA synthetase from E. coli with phenylalanyl-tRNA 
using the method of small-angle X-ray scattering, Mol. Biol. (USSR), 
22: 1623-1631, 1988.

Tuzikov, F.V., Zinoviev, V.V., Vavilin, V.I., Malygin, E.G., Buryanov, Ya.I., 
Bayev, A.A.  Interaction of Eco dam methylase with double-stranded 
desoxyribooligonucleotide,  Dokl. Akad. Nauk SSSR, 304: 231-234, 1989.

Zinoviev, V.V., Rechkunova, N.I., Gorbunov, Yu.A., Tuzikov, F.V., 
Vavilin, V.I., Malygin, E.G.  Studies on the role of symmetry in the 
specific recognition of DNA by type II restriction and modification 
enzymes, Moscow International Symposium "Molecular organization 
of biological structures" (Moscow, USSR), 2: 283, 1989.

Tuzikov, F.V., Tuzikova, N.A., Vavilin, V.I., Zinoviev, V.V., Malygin E.G.,
Favorova, O.O., Zargarova, T.A., Sudomoina, M.A., Kiselev, L.L. 
Aggregation of tryptophanyl-tRNA synthetase depending on temperature.
Study by small-angle X-ray scattering method, Mol. Biol. (USSR), 
25: 740-751, 1991.

Shalaev, E.Yu., Malakhov, D.V., Kanev, A.N., Kosyakov, V.I., Tuzikov, F.V.,
Varaksin, N.A., Vavilin, V.I.  Study of the phase diagram water fraction
of the system water-glycine-sucrose by DTA and X-ray diffraction methods,
Thermochimica Acta, 196: 213-220, 1992.

Tuzikov, F.V., Zinoviev, V.V., Vavilin, V.I., Malygin, E.G.  Application
of the small-angle X-ray scattering technique for the study of  two-step
 equilibrium enzyme-substrate interactions,  Biopolymers ,
38: 131-139, 1996.

Vavilin, V.I., and Tuzikov, F.V.  Determination of plasma lipoprotein 
profile by small-angle X-ray scattering, 1997 Annual Meeting of 
the American Crystallographic Association, July 19-25, 
St. Louis, USA ( accepted ).
 
Vavilin, V.I., and Tuzikov, F.V.  Small-angle X-ray scattering is an effective 
technique for determining the fraction distribution of human  plasma 
lipoproteins,  Journal of Biochemical and Biophysical Methods ( in press ).


SKILLS

Strong background in applications of SAXS software as well as 
MS Windows 95, MS Word for Windows 95, MS Works, 
Netscape Navigator. Excellent command of written and spoken Russian,
and a working knowledge of English.

PERSONAL DATA

Russia citizen, US permanent resident ( pending ), Social Security 
# 214-47-2690, Employment Authorization # EAC-96-235-54061,
Alien Registration # 71348206.
 
REFERENCES

List of references are available upon request.