Methods and applications in the frontier between MX and CryoEM

All events for this Day

Event Name

Methods and applications in the frontier between MX and CryoEM

Start Date 19th Sep 2017
End Date 21st Sep 2017
Description

Session I – Overview and principles

An overview of cryoEM: Richard Henderson (LMB-MRC, Cambridge, UK)

A Bayesian view on cryo-EM structure determination: Sjors Scheres (LMB-MRC, Cambridge, UK)

From hybrid methods to direct structure solving by cryoEM: a Spanish perspective: Jose López Carrascosa (CNB-CSIC, Madrid)

How to overcome biochemical limitations in sample preparation for high-resolution structure determination of macromolecular complexes by cryo-EM and X-ray crystallography: Holger Stark (MPIBPC, Göttingen, Germany)

Session II – Solution and reconstruction

EM reconstruction from the standpoint of Maximum Entropy estimation: Jorge Navaza (CNRS Emeritus at the École Normale Supériere de Cachan)

Solving X-ray crystal structures with cryo-EM reconstructions: Randy Read (CIMR, University of Cambridge, UK)

Repurposing molecular replacement algorithms for docking models in Cryo-EM reconstructions: Airlie McCoy (CIMR, University of Cambridge, UK)

Model-building in Low Resolution and Cryo-EM maps using Coot: Paul Emsley

Session III – Model Building to automation

Automated model building in cryoEM maps: Jon Agirre (YSBL, University of York, UK)

New approaches to the analysis of cryoEM maps quality:José María Carazo (CNB-CSIC, Madrid)

Structural studies of heterogeneous assemblies: Elena Orlova

Model-building using cryo-EM and crystallographic maps: Tom Terwilliger (Los Alamos National Laboratory, USA

Session IV – Refinement and Global Initiatives

 Refinement of atomic models into cryo-EM maps using REFMAC5: Garib Murshudov (LMC-MRC, Cambridge, UK).

New real space refinement methods for cryo-EM: Pavel Afonine (Lawrence Berkeley National Laboratory, Berkeley CA, USA)

The intersection of crystallography and cryo-EM in Phenix, new tools for both: Paul Adams (Lawrence Berkeley National Laboratory, Berkeley CA, USA)

Introducing the Collaborative Computational Project for Electron cryo-Microscopy: CCP-EM: Tom Burnley (CCPEM, UK)

Session V – Application and Future prospects

Investigating membrane protein structure and function by cryo-EM: Werner Kühlbrandt (Max-Plank Institut für Biophysik)

The emerging role of CryoEM in drug discovery and development: Paula da Fonseca (LMB-MRC, UK)

Cryo-EM at near-atomic resolution of icosahedral viruses: José Castón (CNB-CSIC, Madrid)

CryoEM illuminates the world of the Picornaviruses: Abhay Kotecha (Division of Structural biology, University of Oxford, UK)

Mechanistic insights on DNA replication and repair by cryo-EM: Rafael Fernandez Leiro (LMB-MRC, UK)

Structural studies of functional ribosome complexes: Paola Fucini (CIC-Biogune, Bilbao)

 

 

 

 

 

Location Barcelona
Spain
Contact
mx-cryoem-bcn@ibmb.csic.es
URL http://www.sbu.csic.es/conference-mx-cryoem-bcn/
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Category Conferences
Topics Biological macromolecules | Cryo electron microscopy