Event Name

Nucleation - a Transition State to the Directed Assembley of Materials. Faraday Discussion.

Start Date 30th Mar 2015
End Date 1st Apr 2015


The crystallisation phase transformation process and the resulting creation of crystalline materials from liquid phase precursors are central to the science and process engineering of materials in their broadest sense. Crystallisation involves two distinct stages: nucleation and growth. Due to the nano-scale size domain within which the nucleation process functions it is a much less understood process compared to the growth process. As a result, elucidating the fundamental physics and chemistry that govern the formation and structure of the nucleation supra-molecular transition state remains one of the truly unresolved 'grand challenges' of the physical sciences.


The Faraday Division have been organising high impact Faraday Discussions in rapidly developing areas of physical chemistry and its interfaces with other scientific disciplines for over 100 years. 

Faraday Discussions have a special format where research papers written by the speakers are distributed to all participants before the meeting, and most of the meeting is devoted to discussing the papers. Everyone contributes to the discussion - including presenting their own relevant research. The research papers and a record of the discussion are published in the journal Faraday Discussions


  • Molecular self-assembly in nucleation 
    This session will focus on the transition pathway, and its associated molecular assembly process, for solute molecules as they aggregate and stabilise into clusters prior to their subsequent development in the growth stage into facetted crystals. The session will seek to examine the latest results from both experimental studies and advanced molecular and synthonic modelling. 

  • Nucleation kinetics and mechanisms 
    The session will focus on the mechanistic processes underpinning the nucleation process, i.e. whether single/2-step, progressive/instantaneous, homo/heterogeneous etc. and The role played by secondary nucleation processes in modifying nucleation behaviour will be examined and the session will also seek to examine the latest research in kinetic modelling of the nucleation process. 

  • Solvent interactions as determinants in the nucleation pathway 
    This session will seek to examine the role played by crystallisation environment, notably solvent choice (whether polar/apolar, protic/aprotic and molecular size/shape) and resultant solution structure, in dictating the nucleation process. The role played by solution ideality as well as the influence hydrogen bonding and synthon architectures for directing specific solute-solute interactions will be examined.

  • Nucleation in complex multi-component and multi-phase systems 
    This session will examine nucleation within complex crystallisation environments for situation where the presence of multi-components and phases are found to significantly change crystallisation behaviour and crystallisability of a material, e.g. in an extreme case leading to oiling out. Understanding the influence of phase composition, molecular speciation and chirality on behaviour and how this effects the solid form properties of the resultant crystals produced (polymorphic form, crystal size and crystallinity) will be also examined. 


This meeting aims to bring together this growing body of theoretical and experimental work from both the academic and industrial spheres in order to assess recent progress, highlight on-going challenges in the domain area and route-map future work still needed.

Location Leeds
United Kingdom
Contact RSC Events
URL http://www.rsc.org/ConferencesAndEvents/RSCConferences/FD/Nucleation-FD2015/index.asp

Category Seminars
Topics Crystal growth | General | Materials