The Buccaneer software for automated model building.
1. Tracing protein chains

Acta Cryst. (2006). D62, 1002–1011 [doi.org/10.1107/S0907444906022116]

The manual fitting of an atomic model into a 3-d electron density map is a time consuming process, which is being automated by a number of projects. A new technique is described to identify likely candidate C^α positions and then grow these into connected protein chains. Instead of relying on specific features observed in density maps at a particular resolution, the program generates a problem specific statistical target for finding C^α positions in maps matching the map to be interpreted.

K. Cowtan