IUCr journals

Rotational order-disorder structure of fluorescent protein FP480

S. Pletnev, K.S. Morozova, V.V. Verkhusha and Z. Dauter

Application of general formulas for the correction of a lattice-translocation defect in crystals of a lentiviral integrase in complex with LEDGF

S. Hare, P. Cherepanov and J. Wang

Analysis of lattice-translocation disorder in the layered hexagonal structure of carboxysome shell protein CsoS1C

Y. Tsai, M.R. Sawaya and T.O. Yeates

Acta Cryst. (2009). D65, 906–912 (doi.org/10.1107/S0907444909020927); 966–973 (doi.org/10.1107/S0907444909023695); 980–988 (doi.org/10.1107/S0907444909025153)

Three instances are reported of protein crystals exhibiting different kinds of order-disorder phenomena. These types of disorder are distinct from twinning, and might be unfamiliar to macromolecular crystallographers. Hare et al. and Tsai et al. both report crystals containing multiple distinct lattices related by discrete translation vectors, a situation referred to as lattice translocation disorder, while Pletnev et al. describes a different situation in which layers of molecules related by a 90° rotation appear stochastically throughout the crystal. Various treatments are discussed for handling this class of problems.