On the cover
The X-ray fiber diffraction pattern from L and R-type flagellar filaments and the refined electron density map of the R-type filament (an end on view of a 50 Å thick cross section) are esthetically peasing and information rich. Bacteria swim by rotating flagellar filaments. During the straight swimming phase, the flagellar filaments form a bundle behind the cell body, where the filaments are all in a left-handed supercoiled form, each acting as a propellar driven by a rotary motor at the base of the filament. The flagellar filament is a tubular structure composed of 11 protofilament strands, which are axially aligned arrays of subunits. Bacterial motility involves switching between the left and right supercoiled states of the flagellar filament. The 9 Å resolution electron density map of the R-type filament, refined from the X-ray data, reveals details of the supercoil important to bacterial mobility.
Reference: I. Yamashita, K.Hasegawa, H. Suzuki, F. Vonderviszr, Y. Mimori-Kiyosue and K. Namba. Nature Structural Biology, Vol. 5, No. 2, 1998, pp 125-129.
Editorial and production
William L. Duax Editor
X. Bu, J.C. Cassatt, M. Cassman, B. Cernik, A.E. Cordero Borboa, E. Crawford, J.D. Dunitz, C. Ferrero, C. Gilmore, M. Guss, J. Hasek, F.H. Herbstein, R. Hoffmann, W.M. Itano, W. Kamitakahara, R. Lewin Sime, I. Madsen, L. Makowski, R.E. Marsh, M. Martinez-Ripoll, R. Millane, K. Namba, S. Norval, J.C. Norvell, I. Olovsson, P.C. Preusch, C. Rischel, L. Strouts, I. Swainson, M. Walker