Miscellany

Anything they can do...

A mass spectrometry technique for identifying folding patterns of proteins that is potentially faster and requires less sample than x-ray crystallographic or NMR structural methods has been developed by Irwin D. Kuntz who believes the time needed to determine the fold family of a protein can be reduced to one week and the amount of protein required reduced to less than 10 μg. The technique may provide sufficient resolution to elucidate function, conformational states, macromolecular interactions, and leads for the design of protein mimetics.

C & E News, June 5, 2000