Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry

In this review IUCrJ. (2017), 4, 308-321 on the occasion of the award of the 2017 Ewald Prize by the IUCr, I present a personal view of the relationship between academia and industry in the development of structure-guided drug discovery.

Introducing the Proceedings of the CCP-EM Spring Symposium

The Proceedings of the CCP-EM Spring Symposium have been published in Acta Crystallographica Section D: Structural Biology http://journals.iucr.org/d/issues/2017/06/00/index.html. The symposium is an annual conference which aims to review and highlight state-of-the-art developments in macromolecular cyro-electron microscopy in an accessible and convivial manner.

A large-solid-angle X-ray Raman scattering spectrometer

S. Huotari and co-workers J.Sync. Rad. (2017), 24, 521-530 describe an end-station for X-ray Raman spectroscopy at beamline ID20 of the European Synchrotron Radiation Facility. The end-station is dedicated to the study of shallow core electronic excitations using non-resonant inelastic X-ray scattering.

In-cell NMR: a topical review

In-cell NMR has emerged in the past decade as a unique approach to obtain structural and functional information on biological macromolecules within living cells at atomic resolution.

NMR Crystallography

David Bryce and Francis Taulelle introduce a special issue of Acta Crystallographica Section C on NMR Crystallography where the contributions serve as an excellent introduction to the power and scope of NMR crystallographic methods and applications.