Situs
Entered: Wed Dec 15 2010
Operating systems: Irix; Unix
Type: Source
Languages:
Distribution: Free
Application fields: Biology
Bibliography: Wriggers, W., Milligan, R.A. & McCammon, J.A. (1999). J. Struct. Biol. 125, 185–195.
Description: Program package for the docking of protein crystal structures to single-molecule, low-resolution maps from electron microscopy. Developed to provide a robust and quantitative method for the localization of biomolecular subunits in low-resolution data. Use of single-molecule density maps that can be obtained by subtraction of maps from specimens of variable subunit composition. The central algorithm is a topology-representing neural network to correlate features within the structural data sets.