E0378

GLUCOSE 6-PHOSPHATE DEHYDROGENASE: LINKS BETWEEN STRUCTURE AND DEFICIENCY. CE Naylor, AK Basak, S Gover, PJ Mason and MJ Adams

Glucose 6-phosphate dehydrogenase (G6PD) deficiency is the world's most common genetic disease. It affects an estimated 400 million people. The symptoms stretch from the minor (acute haemolytic attacks triggered by a variety of sources) to the severe (chronic non-spherocytic haemolytic anaemia).