E0677

BEYOND ROUTINE STRUCTURE DETERMINATION - THE RENAISSANCE OF SMALL MOIETY CRYSTALLOGRAPHY. A. Alan Pinkerton, Department of Chemistry, University of Toledo, Toledo, OH 43606, USA

The introduction of area detectors, especially the CCD detector, into small moiety crystallography coupled with the availability of powerful, low cost workstations will have as large an impact on the discipline as that made by the introduction of automated diffractometers a quarter of a century ago. In the short term this will lead to a quantum jump in the number of routine structures determined each year. In the long term, crystallographers will devise new experiments and directions to take advantage of this technological advance. A number of potential new directions will be presented. This discussion will be based in part on experiences in my own laboratory and in part by gazing into a crystal ball (pun intended).