Session Chair: Ian Wilson
Dept. Of Mol. Biology
The Scripps Research Inst. MB13
10666 N. Torrey Pines Rd
La Jolla CA 92037
Phone: 619 554 9706
Fax: 619 554 6105
wilson@scripps.edu
Program Contact: I. Wilson
Dept. Of Mol. Biology
The Scripps Research Inst. MB 13
10666 N. Torrey Pines Rd.
La Jolla CA 92307
FAX 619 554 6105
wilson@scripps.edu
(S0302) MS04.10.01
Date: Wednesday, August 14, Time: 3:40 - 4:00, Room: 6B
CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF THE HUMAN ERYTHROPOIETIN RECEPTOR AND AN AGONIST PEPTIDE
Oded Livnah , Enrico A. Sutra, Dana L. Johnson, Linda K. Jolliffe and Ian A. Wilson
(E0733) MS04.10.02
Date: Wednesday, August 14, Time: 4:00 - 4:20, Room: 6B
THREE-DIMENTIONAL STRUCTURE OF HUMAN INTERFERON-GAMMA COMPLEXED TO ITS CELL RECEPTOR
Daniel Thiel , Marie Le Du, Richard Walter, Allan D'Arcy, Christiane Chene, Michael Fontoulakis, Gianni Garotta, Fritz Winkler and Steve Ealick
thiel@msc.cornell.edu
(S0344) MS04.10.03
Date: Wednesday, August 14, Time: 4:20 - 4:40, Room: 6B
REFINED STRUCTURES OF HETEROTRIMERIC G PROTEIN COMPLEXES AT HIGH RESOLUTION
John Sondek , Andrew Bohm, David G. Lambright, Nikolai P. Skiba, Joseph P. Noell, Heidi E. Hamm and Paul B. Sigler
sondek@scbarg.med.yale.edu
(D0076) MS04.10.04
Date: Wednesday, August 14, Time: 4:40 - 4:50, Room: 6B
STRUCTURAL ANALYSIS OF A DIMERIC STATE OF THE FIRST INTRACELLULAR DOMAIN OF PTPA, A PROTEIN RECEPTOR-LIKE TYROSINE PHOSPHATASE
Alexandrine Bilwes , J. Den Hertog,, T. Hunter and J.P. Noel
(D0126) MS04.10.05
Date: Wednesday, August 14, Time: 4:50 - 5:00, Room: 6B
PH DOMAINS: DIVERSE SEQUENCES WITH A COMMON MEMBRANE ASSOCIATION FUNCTION
Kathryn M. Ferguson , Mark A. Lemmon, Joseph Schlessinger and Paul B. Sigler
ferguson@csbarg.med.yale.edu
(S0551) MS04.10.06
Date: Wednesday, August 14, Time: 5:00 - 5:10, Room: 6B
ARCHITECTURE AND INTRASTERIC REGULATION OF GIANT PROTEIN KINASES
B. Kobe , J. Heierhorst, S.C. Feil, M.W. Parker, G.M. Benian and B.E. Kemp
u5632967@ucsvc.ucs.unimello.edu.au
(E0527) MS04.10.07
Date: Wednesday, August 14, Time: 5:10 - 5:20, Room: 6B
CRYSTAL STRUCTURE OF A HISTIDINE KINASE DOMAIN OF THE ANAEROBIC SENSOR PROTEIN ARCB FROM E COLI
Toshio Hakoshima , Masato Kato, Toshiyki Shimizu, Kazuya Ishige and Takeshi Mizuno
hakosima@bs.aist-nara.ac.jp
(S0263) MS04.10.08
Date: Wednesday, August 14, Time: 5:20 - 5:35, Room: 6B
STRUCTURE OF THE PHOSPHORYLATED FORM OF THE CDK2:CYCLIN-A COMPLEX
Philip D. Jeffrey , Alicia A. Russo and Nikola P. Pavletich
phil@xray2.mskcc.org
(E1070) MS04.10.09
Date: Wednesday, August 14, Time: 5:35 - 6:00, Room: 6B
HORMONE BINDING TO THE THYROID HORMONE RECEPTOR
R. Fletterick , R. Wagner, J. Baxter, A. Shiau and J. Apriletti
flett@msg.ucsf.edu
(S0573) PS04.10.10
Session: III, Board: 053, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF mTNF
Katrien Baeyens , P. Brouckaert, A. Raeymaekers, W. Fiers, C.J. De Ranter and H.L. DeBondt
(E0787) PS04.10.11
Session: III, Board: 054, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF CheR, BACTERIAL CHEMOTAXIS RECEPTOR METHYLTRANSFERASE
Snezana Djordjevic and Ann Stock
djordjevic@mbcl.rutgers.edu
(D0011) PS04.10.12
Session: III, Board: 055, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF THE pH2 DOMAIN OF THE PROTEIN SHC: PH-DEPENDENT SELF-ASSOCIATION
Klaus Ftterer , Stphane Rty, Richard A. Grucza and Gabriel Waksman
klaus@gwiris1.wustl.edu
(S0343) PS04.10.13
Session: III, Board: 056, Room: Not Yet Assigned
STRUCTURE AND INPORTANCE OF THE DIMERIZATION DOMAIN IN ELONGATION FACTOR TS FROM THERMOS THERMOPHILUS
Youxing Jiang , Steffan Nock, Martina Nesper, Mathias Sprinz and Paul B. Sigler
youxing@csbarg.med.yale.edu
(S0424) PS04.10.14
Session: III, Board: 057, Room: Not Yet Assigned
YEAST CYTOSOLIC CYCLOPHILIN A AS ANALOGY OF HUMAN ISOFORM
Michiko Konno , Sawako Fujioka and Akiko Kashima
konno@ts.cc.ocha.ac.jp
(S0447) PS04.10.15
Session: III, Board: 058, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF A PHOSPHATASE RESISTANT MUTANT OF SPORULATIN RESPONSE REGULATOR Spo0F FROM BACILLUS SUBTILIS
Madhusudan , John M. Whiteley, James A. Hoch, James Zapf, Nguyen H. Xuong and Kottayil I. Varughese
mhusudan@scripps.edu
(E0684) PS04.10.16
Session: III, Board: 059, Room: Not Yet Assigned
A DOMINANT-NEGATIVE MUTANT OF E COLI MALTOSE-BINDING PROTEIN: X-RAY STRUCTURES AND GENERAL LESSONS
Sherry L. Mowbray and Brian H. Shilton
mowbray@xray.bmc.uu.se
(E1140) PS04.10.17
Session: III, Board: 060, Room: Not Yet Assigned
CELL CYCLE PROTEINS
M.E. Noble , J.A. Endicott, N.R. Brown, E. Garman, R. Dzivenu, A. Lawrie, L.N. Johnson, P. Nurse and R.T. Hunt
martin@biop.ox.ac.uk
(E1261) PS04.10.18
Session: III, Board: 061, Room: Not Yet Assigned
CRYSTALLOGRAPHIC AND BIOCHEMICAL ANALYSIS OF AN INHIBITOR OF APOPTOSIS, BCL-2
Jason W. O'Neill and Kam Zhang
joneill@fred.fhcrc.org
(S0615) PR04.10.19
THE STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE-1B COMPLEXED TO A HIGH AFFINITY INHIBITOR
Andrew D. B. Pannifer , Terrence R. Burke Jr. and David Barford
andrewp@biop.ox.ac.uk
(E1182) PS04.10.20
Session: III, Board: 063, Room: Not Yet Assigned
CRYSTALLOGRAPHIC ANALYSIS OF A FRAGMENT FROM CHICKEN TENASCIN CONTAINING TWO FIBRONECTIN-TYPE III DOMAINS
Klaus Piontek , Daniel Bisig, Peter Weber, Lloyd Vaughan and Kaspar Winterhalter
piontek@wawona.vmsmail.ethz.ch
(S0398) PR04.10.21
CURRENT PROGRESS ON CRYSTALLOGRAPHIC COMPLEXES OF TRANSDUCIN
Susan M. Redford , Heidi Hamm and Joseph Noel
susan@sbl.salk.edu
(E0624) PS04.10.22
Session: III, Board: 065, Room: Not Yet Assigned
REFINED CRYSTAL STRUCTURES OF TNF-ALPHA AND TNF MUTANT R31D
C. Reed , Z.-Q. Fu, J. Wu, Y.N. Xue, M.-J. Chen and I. T. Weber
reed@asterix.jci.tju.edu
(E0706) PS04.10.23
Session: III, Board: 066, Room: Not Yet Assigned
REFINEMENT OF NATIVE AND MUTANT VEROTOXIN B-SUBUNIT STRUCTURES
Allan M. Sharp , Penelope E. Stein, Amechand Boodhoo and Randy J. Read
allan@mycroft.mmid.ualberta.ca
(E1376) PS04.10.24
Session: III, Board: 067, Room: Not Yet Assigned
ATOMIC STRUCTURE OF POTD - THE PRIMARY RECEPTOR OF SPERMIDINE/PUTRESCINE TRANSPORT SYSTEM IN E COLI
D.G. Vassylyev , S. Sugiyama, M. Matsushima, T. Kashiwagi, K. Igarashi and K. Morikawa
dmitry@xg1.beri.co.jp
(S0454) PS04.10.25
Session: III, Board: 068, Room: Not Yet Assigned
CRYSTALLOGRAPHIC ANALYSIS OF THE MAP KINASE P38
Zhulun Wang , Jiahuai Han and Elizabeth J. Goldsmith
zhulun@grate.swmed.edu
(E1230) PS04.10.26
Session: III, Board: 069, Room: Not Yet Assigned
17 STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85 SUBUNIT OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE
Simon Weston , Dean Derbyshire, Alex Breeze and Richard Pauptit
weston@zeneca-ph.co.uk
(E0229) PR04.10.27
CRYSTAL STRUCTURE OF HUMAN INTERLEUKIN-10 AT 16 RESOLUTION
Alexander Zdanov , Celine Schalk-Hihi and Alexander Wlodawer
sasha@crysv1.ncifcrf.gov
(E0291) PR04.10.28
COMBINED STUDY OF PURINERGIC TRANSDUCTION USING CRYSTALLOGRAPIC AND ELECTROPHYSIOLOGICAL TECHNIQUES
V. A. Panchenko , F. Rodriques-Pascual, M. T. Miras-Portugal and O. A. Krishtal
bipukas@sovam.com
(E1488) PS04.10.29
Session: III, Board: 071, Room: Not Yet Assigned
PRELIMINARY DIFFRACTION STUDIES OF THE REGULATED FORM OF CHICKEN SRC PROTEIN TYROSINE KINASE
J.C. Williams , A. Weijland, S.A. Courtneidge, G. Superti-Furga and R.K. Wierenga
jwilliam@embl-heidelberg.de
(E1514) PS04.10.30
Session: III, Board: 072, Room: Not Yet Assigned
STRUCTURES OF ELONGATION FACTOR TU-GDP COMPLEXED TO ANTIBIOTICS: GE2270 AND TETRACYCLINE
Kenton Abeln , Suet Mui, Marilyn Yoder and Frances Jurnak
(E1513) PS04.10.31
Session: III, Board: 073, Room: Not Yet Assigned
THREE-DIMENSIONAL STRUCTURE OF THE E. COLI ELONGATION FACTOR TU-TS COMPLEX AT RESOLUTION OF 2.3
Susan Heffron , Jacqueline Vitali, Brian Schick, Kenton Abel and Frances Jurnak
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