Summer cryo-EM data processing workshop

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Event Name

Summer cryo-EM data processing workshop

Start Date 24th Jun 2018
End Date 28th Jun 2018

Recent technological developments in microscopes, cameras, and computation have led to a “resolution revolution” in the field of cryo-EM, making it possible to determine 3-D structures below a three-angstrom resolution.

The focus of the program — which runs June 24 to June 28 — is to introduce participants to common image processing packages used to analyze cryo-EM data. This is a hands-on opportunity where trainees will work with instructors to learn how to independently use cryo-EM software packages including cisTEM, cryoSPARC, RELION and Rosetta. Prior experience analyzing cryo-EM data will be helpful as the course is focused on providing participants with practical data processing experience.

The workshop is co-sponsored by Thermo Fisher Scientific, the manufacturer of the four cryo-EM microscopes used at the LSI’s world-class facility. Since its introduction ten years ago, the Thermo Scientific Krios cryo-EM system has proven its ability to visualize three-dimensional structures with near-atomic resolution. This has enabled researchers globally to begin unravelling the complex relationships between structure and function at the molecular and atomic levels.

Instructors of the program include LSI faculty members Michael Cianfrocco, Ph.D., and Melanie Ohi, Ph.D.

Guest lecturers include Xiaochen Bai, UT Southwestern; Alexis Rohou, Genentech; Zev Ripstein from the laboratory of John Rubinstein at the University of Toronto; and Frank Dimaio, University of Washington.

Location Ann Arbor, MI
United States
Contact Michael Cianfrocco

Category Workshops
Topics Cryo electron microscopy