Newsletter

search results

results of search on CRYSTALLOGRAPHY JOURNALS ONLINE

46 citations found for Ida,

Search for Ida, in the World Directory of Crystallographers

Select bibliographic records for downloading using the checkboxes or select all button

Results 1 to 20, sorted by name:


Download citation
Acta Cryst. (2017). A73, C991
Download citation


Download citation
Acta Cryst. (2014). A70, C847
Download citation

link to html
[gamma]-Glutamyltranspeptidase (GGT; EC 2.3.2.2) is involved in the degradation of [gamma]-glutamyl compounds such as glutathione (GSH; [gamma]-glutamyl-cysteinyl-glycine) . A major physiological role of this enzyme is to cleave the extracellular GSH as a source of cysteine for intracellular glutathione biosynthesis. Another crucial role of GGT is to cleave glutathione-S-conjugates as a key step in detoxification of xenobiotics and drug metabolism. In mammals, GGT has been implicated in physiological disorders such as Parkinson's disease, other neurodegenerative diseases including Alzheimer's disease and cardiovascular disease. The indispensable roles played by GGT in GSH-mediated detoxification and cellular response to oxidative stress suggest that GGT is an attractive pharmaceutical target. We here report the binding mode of acivicin, a well-known glutamine antagonist, to B. subtilis GGT at 1.8 Å resolution showing that acivicin is bound to the O[gamma] atom of Thr403, the catalytic nucleophile of the enzyme, through its C3 atom [1]. The observed electron density around the C3 atom was best fitted to the planar and sp2 hybridized carbon, consistent with a simple nucleophilic substitution of Cl at the imino carbon by O[gamma] atom of Thr403. Furthermore, comparison of three bacterial enzymes, the GGTs from E. coli, H. pylori and B. subtilis in complex with acivicin, showed significant diversity in the orientation of the dihydroisoxazole ring among three GGTs. The differences are discussed in terms of the recognition of the [alpha]-amino and [alpha]-carboxy groups in preference to the dihydroisoxazole ring as observed in time-lapse soaking crystal structures of B. subtilis GGT with acivicin.

Download citation
Acta Cryst. (2008). A64, C505
Download citation



Download citation
Acta Cryst. (2005). A61, c194
Download citation


Download citation
Download citation

link to html
Monoclinic crystals of N. alata SF11-RNase have been obtained. Native data have been collected to 1.55 Å resolution using the SPring-8 synchrotron-radiation source.

Download citation
Download citation

link to html
Mathematical formulae of the flat-specimen effect in powder diffractometry with Bragg-Brentano geometry are examined.

Download citation
Download citation

link to html
A formula of the instrumental function for a synchrotron X-ray diffractometer has been derived. The experimental profiles of standard Si powder are well reproduced by the model profile function given by the convolution of a Lorentzian function with the instrumental function, within experimental uncertainty.

Download citation
Download citation

link to html
Efficiency in the calculation of absorption corrections for cylinders has been examined. Application of the Gauss-Legendre quadrature to the formula proposed by Thorkildsen and Larsen gives results having a relative error [less-than or equal to]10-6 with 12 × 12 terms in the numerical integrals.

Download citation
Download citation

link to html
Particle statistics in synchrotron powder diffractometry measured in a capillary transmission mode have been theoretically and experimentally investigated. It is shown that the size distribution of crystallites of about several micrometres can be evaluated by applying a spinner-scan method.

Download citation
Acta Cryst. (2008). A64, C198
Download citation


Download citation
Download citation

link to html

Download citation
Download citation

link to html
An analytical method to obtain symmetric peak profiles from experimental data with asymmetric peak profiles measured with a high-resolution synchrotron X-ray powder diffractometer has been developed. The method has successfully been applied to the diffraction intensity profiles of a ZnO powder sample measured with a synchrotron X-ray powder diffractometer on beamline BL4B2 at the Photon Factory.

Download citation
Download citation

link to html
Models for counting losses in X-ray detection systems are examined. A convenient and versatile formula for correcting count losses is presented.

Download citation
Download citation

link to html
A novel method to deconvolute the instrumental aberration functions from the experimental powder X-ray data has been developed. The effects of axial divergence, flat specimen, sample transparency and spectroscopic profile of the source X-ray are eliminated from the entire observed diffraction pattern in three-step operations.

Download citation
Download citation

link to html
A new methodology is proposed for structure refinement using powder diffraction data, from which models for particle statistics and any other statistical errors can formally be optimized. Structure parameters optimized by the method tend to become closer to those obtained by a single-crystal method as compared with results from the Rietveld method.

Download citation
Download citation

link to html
A method to deconvolute the instrumental aberration functions from the experimental powder X-ray data measured with a high-resolution synchrotron powder diffractometer has been developed. The effects of the diffractometer aberration and asymmetry caused by the beamline optics have been eliminated from the entire observed diffraction pattern of LaB6 powder.

Download citation
Download citation

link to html
Mathematical formulae for the effect of sample transparency in powder diffractometry with Bragg-Brentano geometry are examined. The overall profile function given by triple convolution of the pseudo-Voigt function with the horizontal divergence, sample transparency and vertical divergence aberration functions reproduces the experimental peak profiles well.

Download citation
Download citation

link to html
The statistical properties of X-ray intensities measured with counting systems were experimentally investigated by repeated measurements based on Chipman's foil method. It is shown that the observed statistical variance can be well reproduced by a formula derived from an intermediately extended dead-time model for counting loss.

Download citation
Download citation

link to html
A Fourier method to connect segmented intensity data measured with a multiple-detector system for powder diffractometry has been developed. The method enables the correction of the differences in instrumental functions of different detectors.

Follow IUCr Journals
Sign up for e-alerts
Follow IUCr on Twitter
Follow us on facebook
Sign up for RSS feeds