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7 citations found for Stoddard, B.L.

There are 8 articles by Stoddard, B. click here to see these.

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The gene encoding iron superoxide dismutase from P. ovalis has been cloned and sequenced; the recombinant enzyme has been crystallized and its structure determined.

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A crystallization strategy termed `microseed matrix screening' is described where the optimal conditions for nucleation versus extended lattice growth are not compatible.


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Recombinant bacterial cytosine deaminase from Escherichia coli has been subcloned, overexpressed, purified and crystallized for structural analysis. The crystals belong to space group R32, with unit-cell parameters a = b = 109.1, c = 240 Å and diffract to at least 1.5 Å resolution at a synchrotron X-ray source.

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A simple quantitative method, based on visible absorbances in the crystal measured by digital image analysis, is described for measuring diffusion and binding in the crystal.

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Major developments in the theory of the Laue diffraction technique and of the necessary software, hardware and experimental strategies have led to successful time-resolved studies on the dynamic properties of a range of biological systems, which shed light on future applications of this technique.


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