MXIS 2017: Practical course on in-plate crystallography, with special focus on ligand screening. Part 1

Part 2: 29 Nov. - 1 Dec., at the EPN campus, Grenoble, France The MXIS training course is dedicated to in situ protein crystallography, with a special emphasis on ligand screening. This workshop is organized in two parts, each one lasting for 3 days. It includes:

• Part 1 (Montpellier): full lectures at the “Centre de Biochime Structurale” followed by practicals. Topics: plate pre-coating for “Dry” co-crystallization [1], in situ screening on a lab source).
• Part 2 (Grenoble): full lectures at the “Institut de Biologie Structurale” and practical sessions at the ESRF, on beamlines FIP-BM30A and ID30B. Full classes will be done in day 1 while practical sessions will be organized in subgroups, from day 2 to day 3. Topics: in situ diffraction for crystal screening and structure resolution, in situ data processing.

Possibility will be given to participants to practice on their own samples. A fragment library may be available to be used on your sample (to be confirmed later on)

The workshop is limited to 6 and 8 participants for Part 1 and 2 respectively.

No fees are required.

The application period will close on the 8th of October. Applicants will be required to submit a short CV and a motivation letter to [email protected]