Icknield Model Building Workshop

This is a comprehensive course for EM model building covering advanced use of ARP/wARP Buccaneer, CCP-EM, Coot, FlexEM, ISOLDE, LocScale, MolProbity, Refmac. The course is designed such that applicants bring their own 'live' high resolution datasets to work on with the developers during the workshop.

Tutors and topics include:

Tristan Croll (Cambridge)
ISOLDE: Interactive model building/real-space refinement based on interactive Molecular Dynamics

Grzegorz Chojnowski (Lamzin group, EMBL)
ARP/wARP: Automated model building of protein structures

Kevin Cowtan (York)
Buccaneer: Automated model building

Paul Emsley (MRC-LMB Cambridge)
Judit Debreczeni (AstraZeneca)
Coot: Macromolecular model building, model completion and validation

Arjen Jakobi (TU Delft)
LocScale: reference-based density scaling for local sharpening of cryo-EM maps

Jane Richardson (Duke)
MolProbity: All-atom structure validation

Garib Murshudov (MRC-LMB Cambridge)
Rangana Warshamanage (MRC-LMB)
Refmac: Refinement of high-resolution EM structures

Osman Salih (EBI)
EMBD: Deposition in EMBD

Agnel Joseph (CCP-EM, STFC) & Sony Malhotra (Topf Group, Birkbeck)
FlexEM: Fitting and refinement of atomic structures guided by cryoEM density