X-PLOR

Simulated annealing refinement. The new release, X-PLOR 98.0 offers substantial new capabilities for both X-ray crystallographic and NMR structure refinement including: maximum likelihood methods for X-ray structure refinement; optimized torsion angle dynamic (TAD) methods; Validated scripts for TAD with NMR distance restraints; ambiguous restraints for iterative assignment (ARIA) technology; novel technology for NOE refinement.