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Crystallization: Focus on Membrane Proteins

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In Brookhaven, NY

Biological macromolecules Crystal growth

Purpose and Scope of Workshop

The purpose of this course is to provide participants with hands-on experience of a variety of crystal growth methods for obtaining high quality crystals. The course will address both conventional and non-conventional methods in membrane protein crystal growth. Optimization methods will include application of oils, novel nucleating agents, detergents, crystallization in lipid cubic phase, crystallization with gels, and more... Introductory lectures will precede the eight practical sessions planned for the course. Time for discussions and informal meetings with the tutors is scheduled.
A special session on cryogenic protection and crystal quality assessment will be conducted at the X6A beam line on the last day.

Intended Audience

Graduate students, post-doctoral fellows and research scientists interested in learning about different approaches to crystallization.