3rd Grenoble Practical Workshop on Helical Symmetry determination and reconstruction

The third edition of the Grenoble practical workshop focused on the determination of helical symmetry in biological polymers imaged by cryo-EM will take place online from 
July 21st to 25th, 2025.
Ed Egelman and Arjen Jakobi will be speakers, whose expertise will greatly enrich both our discussions and hands-on sessions.

While *Helixplorer* (https://urldefense.com/v3/__https://rico.ibs.fr/helixplorer/__;!!Mih3wA!E8k6u4PapE61RoHy1fNa_JmGof9e65JNpZs2Dcf7d1ogbvN9gxduVMX-fpPxMI-nzq_qTqbseDr52Jf6kB_Jv66N9Rjr$ ) will play a central role in our practical sessions, we also encourage participants 
to explore alternative approaches to address a variety of research needs.

Beyond helical parameter determination, we will also explore `broader 
reconstruction strategies', including managing flexible helices, working 
with multiple symmetries, and integrating data from different filament 
symmetries using subtraction techniques.

We welcome applicants at all career stages (PhD students, postdocs, 
senior scientists, and beyond) who are currently working on helical 
samples and facing structural analysis challenges. During the workshop, 
participants will use their own data, sharing selected raw images, 2D 
class averages, and power spectra with the organizers. The specific 
identity and function of your protein or filament will remain confidential.

To apply, please email your application?including a brief description of 
your project and the difficulties you?re encountering, as well as 
screenshots of your raw data and 2D class averages with the 
corresponding *pixel size*? to:

 *[email protected]*

 *[email protected]*

*Application deadline: June 10th.*