Time: Thursday, May 26, 2022 at 9 AM pacific / 12 PM eastern time
From NIH Transformative High Resolution CryoEM Program sponsored service centers

Speakers: Lorena Saelices Gomez & Binh Nguyen, Center for Alzheimer's and Neurodegenerative
Diseases, Department of Biophysics, UT Southwestern Medical Center.

May 19, 2022, 4:00 PM â€" 6:00 PM Warsaw time (Central European Time)

Lecture 10: Christian Jelsch (CNRS & Université de Lorraine, Nancy, France) : "Charge Density & Intermolecular Interactions"

and

Lecture 11: Thomas Barend (Max Planck Institute for Medical Research, Heidelberg, Germany): "Watching Molecules at Work with Free-Electron Lasers"

The lectures are free and open to everyone. Each lecture is expected to last maximum ca. 35min + up to 15min for Q&A. Just make sure to register so that you can attend.

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Date: 17^th of May, 3 PM CETÂ

 Registration link for online event: https://us02web.zoom.us/webinar/register/1516510473839/WN_YKgaC5TES-SkAge_obtD6A

04.00 PM PARIS time

Topic : Watching molecules dancing in the cell. 
After a short journey through the evolution of structural biology and the present state of the art of crystallography and cryo-EM, 
we will show how the combination of optical methods and cryo-tomography open the door to the cell at atomic level. 

Webinar Speaker : 

Dino Moras (UNISTRA, CNRS, IGBMC) 

Next NIH sponsored Joint CryoEM Service Centers Webinar Series

12pm (Eastern Time)

 

Date: 30^th of March, 4.30 PM CET

Speakers:

Prof. Hans Florian Zeilhofer, Delegate for Innovation, University of Basel

Dr. Christoph Boss, Head of Drug Discovery Chemistry, Idorsia

Prof. Michael Hennig, CEO, leadXpro AG
Dr. Mihaela Pop, Chief Scientific Officer TeraCrystal
Dr. Bernd Hinrichsen, Head of Electron Microscopy BASF
Prof. Paulina Dominiak, Group head, University of Warsaw
Dr. Michael Kaufmann, Partner, BOHEST intellectual property
Prof. Christian Lehmann, Group head, MPI für Kohlenforschung

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Presented by Professor Louisa Meshi, Ben-Gurion University Israel at 3pm CET

To be given by Professor Jeroen A. van Bokhoven (ETH & PSI)

Online at 3pm CET

At 4.00pm-6.00pm European/Warsaw time

Lecture 6: Dietmar Stalke: Reactivity and Bonding in Lithium Organics from Charge Density

Lecture 7: Ann-Christin Pöppler - to be confirmed

At 4.00pm-6.00pm Europe/Warsaw time

Lecture 4: Jacob Overgaard: Quantum Crystallography in molecular magnetism

Lecture 5: George Christou: Molecular Nanoparticles: A Molecular Route to Ultra-small Nanoparticles of Important Metal Oxides

Dylan Jayatilaka: Quantum Crystallography: Past, Present, and Future

At 4.00-6.00pm European/Warsaw time

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The 15th webinar in the series, which will be hosted by Instruct Portugal on 14th December 2021, 11:00 - 12:30 CET

The upcoming webinar will feature talks on the application of structural biology methods to better understand key aspects of protein complexes structure and function. The webinar speakers will discuss new drug targets for diseases, with a focus on Mycobacterium tuberculosis. Additional topics include structural biology techniques with Mass Spectrometry and Cryo-EM.

 * Talk 1: Exploring a new drug target against Mycobacterium tuberculosis

Speaker: Hugo Fraga
 * Talk 2: Breaking the limits of native MS with MRMS
Speaker: Carlos Cordeiro
 * Talk 3: Catching up with the CryoEM Resolution Revolution

Speaker: Pedro Matias

Moderator: Maria Arménia Carrondo, Universidade Nova de Lisboa

Determining structural mechanisms of allosteric regulation in ABCC family transporters using a remote cryo-EM pipeline
 

December 9th, 2021 at 12pm (Eastern Time)
 

Registration is at no-cost, but sign-up is required

Determining structural mechanisms of allosteric regulation in ABCC family transporters using a remote cryo-EM pipeline
 

December 9th, 2021 at 12pm (Eastern Time)
 

Registration is at no-cost, but sign-up is required

When: Dec 8, 2021 04:00 PM Paris 

Webinar Speaker Dr. Wladek Minor (Harrison Distinguished Professor, Department of Molecular Physiology and Biological Physics, University of Virginia, USA) 

Topic: Structural Biology Response to Biomedical Threats
 
Register in advance for this webinar: 
https://us06web.zoom.us/webinar/register/WN_KnjC1dDBRZG4r8F6hQ_-VQ 

After registering, you will receive a confirmation email containing information about joining the webinar. 

9 a.m. PST | 12 p.m. EST | 6 p.m. CET
 

In this GEN webinar, our expert panelists will discuss the most recent data on how cryo-EM-enabled structural insights are guiding the development of novel strategies for rational drug design in serotonin (3A) receptors and glycine receptors.

A live Q&A session will follow the presentation, offering you the chance to ask questions and engages with our panelists.

 

Subjecting matter to extreme conditions reveals a multitude of fascinating phenomena, and is applicable to a wide range of disciplines. From the extremophiles that exist in the deepest depths of our oceans to the exotic new materials that are made when atoms are pushed ever closer together, understanding the structure of materials at extreme conditions affects Biology, Chemistry, Physics, Geoscience and Material Science. In order to achieve its goals, high pressure research has been always at the vanguard of technical progress. It is a discipline in which equipment plays a particularly important role. State-of-the-art diamond anvil cells can now achieve megabar ranges of pressure, millions of times atmospheric pressure, with this beaten by an order of magnitude in dynamic compression experiments. In this manner, scientists are able to mimic the conditions in the interiors of giant planets. Nature is even more ambitious, as in the stars petapascal pressures (the order of tens to hundreds billion atmospheres) are reached. In the laboratory, we can even create conditions of pressure, temperature and magnetic fields that are not found naturally, allowing us to complement nature to explore more exotic phases of matter.

Therefore, the course will cover broad ground in the application of extreme conditions crystallography. The topics will span from fundamentals of high-pressure single crystal and powder diffraction, to presenting the many flavors of static and dynamic compression, to reviews of sources for extreme conditions work (synchrotrons, neutrons and free electron lasers). Complementary experimental (Mössbauer spectroscopy, X-ray magnetic circular dichroism, X-ray absorption spectroscopy, inelastic scattering) and computational methods will also be discussed. Diffraction analysis on the structure of liquids, glasses and nanocrystalline materials as well as multigrain crystallography will also be introduced. The lectures will be harmonized with the related sessions of interactive tutorials, providing hands-on experience to the attendees. These workshops will be focused on basic laboratory skills and the elements of data processing software related to the high pressure.