This talk is given by Dr Miao Zhang through the NIH sponsored Joint CryoEM Service Centers Webinar Series

Thursday April 30th, 2026 at 12pm (EASTERN TIME)

Registration is at no-cost, but sign-up is required

 

12:00 PM Eastern (US, Canada) / 5:00 PM GMT (UK)
 

Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling high-resolution visualization of dynamic biomolecular assemblies. However, a central challenge remains: developing robust computational methods to model different forms of structural heterogeneity?including continuous motions, discrete states, and compositional variations and to accurately estimate population distributions.

To encourage the development and benchmarking of heterogeneous reconstruction algorithms and workflows, we invite the cryo-EM community to analyze three new curated experimental and synthetic datasets:

1. Compositional Heterogeneity
2. Conformational Heterogeneity
3. Pose Entanglement

Please join us for a webinar where we will introduce this year's challenge.
Submissions close on June 1, 2026.

Please share this with others who may be interested. We hope you?ll join us for this year?s challenge!

Thursday, October 30, 2025 at 9 AM pacific / 12 PM eastern time

At 4 pm CET.

Lecture 49: The Role of Quantum Crystallography in the Understanding of the Role of Weak Intermolecular Interactions involving Organic Fluorine given Deepak Chopra (Indian Institute of Science Education and Research Bhopal, India).

Lecture 50. Photomechanical molecular crystals as actuators and motors given by Christopher J. Bardeen (Department of Chemistry, University of California, Riverside, USA).

The lectures are free and open to everyone; these particular lectures are expected to last ca 35min + up to 15min for Q&A.

9 AM pacific / 12 PM eastern time

At 4 pm CET

Lecture 47: Quantum Crystallography for Macromolecular Systems: applications and recent developments given by Benoit Guillot (Université de Lorraine, CNRS, Nancy, France)

Lecture 48: Optimal Clustering for Quantum-Based Refinement of Biomacromolecules given by Malgorzata Biczysko (University of Wrocław, Poland), Holger Kruse (Pending AI Pty Ltd., Australia), Nigel W. Moriarty(LBNL, Berkeley, USA), Mark P. Waller (Pending AI Pty Ltd., Australia) and Pavel V. Afonine (LBNL, Berkeley, USA)

Hosted by Clovertex

Date & Time: *March 13 at 11:00 AM EST* (8:00 AM PST | 4:00 PM CET) Format: Roundtable discussion with interactive Q&A

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Panelists: Katie Meze (Sanofi), Roberto Valverde (Renasant Bio), Simone Cavadini (FMI)

Registration: Webinar Registration Page

The focus of the 2025 GRS will be novel approaches in Cryo-Electron Microscopy and Tomography, emphasizing recent advances in hardware and software that enable in situ structural biology. These developments have expanded opportunities to address complex biological questions using multimodal cryo-EM techniques which we will aim to highlight during the meeting. Through engaging sessions and mentorship, attendees can discuss challenges, share solutions, and build networks within the community.

At 4pm CET

Lecture 42: "Chemical Applications of X-ray Quantum Crystallography" by Sajesh Thomas (Department of Chemistry, Indian Institute of Technology, New Delhi, India)

Lecture 43: "Rational Design of Complex Electromechanical Phenomena in Molecular Crystals" by Sarah Guerin (Bernal Institute & Department of Chemical Sciences University of Limerick, Ireland)

At 4 pm CET

Lecture 42: "Chemical Applications of X-ray Quantum Crystallography" by Sajesh Thomas (Department of Chemistry, Indian Institute of Technology, New Delhi, India)

Lecture 43:"Rational Design of Complex Electromechanical Phenomena in Molecular Crystals" by Sarah Guerin (Bernal Institute & Department of Chemical Sciences University of Limerick, Ireland)

 Oct 7, 2024 04:00 PM in LONDON, 8.00-9.30 AM (PDT)

Speakers: Prof. Axel Brunger at Stanford University and Prof. Sarah Haigh at the University of Manchester.

The next NIH sponsored Joint CryoEM Service Centers Webinar Series is at 12pm (Eastern Time) USA, 05:00 PM in London, UK.

Given by Dr Camden Driggers from Oregon Health and Science University.

This webinar will be presented by Claudio Catalano, a senior scientist at NanoImaging Services.

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At 11am PST / 2pm EST. Registration is FREE

Time: Thursday, June 27, 2024 at 9 AM pacific / 12 PM eastern time

Speaker: Dr. Keerthi Gottipati, Indiana University, Bloomington

Title: Cryo-EM structure of HIV-1 Rev Response Element RNA: Structural basis of Rev-RRE interaction
 

All are welcome to attend. Registration is at no-cost, but sign-up is required: