his course is aimed
at structural biologists with high resolution EM maps ready for / in the
process of modelling building and refinement. This three day course will
host some of the leading software developers and provide ample contact time
to allow delegates to discuss their data in detail alongside traditional
lectures and tutorials.

The course will be held at the RAL / Diamond campus, Harwell, UK.
Registration is free and we will provide food and two nights accommodation
at the Bear Hotel in nearby Wantage (5th & 6th April). Delegates are asked
to meet their own travel costs.

The course is limited to 20 delegates which will be selected from all
applicants. A maximum of 40 applicants can register interest.

Applications will close on Sunday 12th March and the 20 successful
applicants will be by Tuesday 14th March. (Please note the short
registration time as we would like to work on 'live' datasets).

A Purdue Mini-symposium on Integrating Structure, Function, and Interactions of the Biomolecular Universe.

This symposium is an interdepartmental event focusing on interdisciplinary research in biophysics and structural biology. The event provides an exceptional platform for students and postdoctoral scholars to present their work, learn about cutting-edge research, and network with young scientists and faculty members from Purdue and regional institutions.

Registration is free, but space is limited.

Instrumentation and Methods (IM)

• IM 1: Advances in instrumentation and methods
• IM 2: Environmental, in-situ and time-resolved microscopy
• IM 3: Image analysis and handling of big data sets
• IM 4:Quantification and modeling
• IM 5: Spectroscopy in microscopy
• IM 6: Tomography
• IM 7: Phase-related techniques
  
  

Life Sciences (LS)

• LS 1: Single particle EM, microscopy of membrane assemblies
• LS 2: From cells to tissues: cellular electron tomography and imaging of large volumes
• LS 3: Microorganisms, pathogens and EM in diagnostics
• LS 4: Subcellular processes in plants and animal cells
• LS 5: Cytoskeleton, cellular traffic and membrane dynamics
• LS 6: Imaging techniques: X-ray microscopy, live/in vivo imaging and correlative approaches
• LS 7: Advances in sample preparation and analysis
  
  

Materials Science (MS)

• MS 1: Functional materials and semiconductors
• MS 2: Interfaces and surfaces, coatings and thin films
• MS 3: Energy-related materials
• MS 4: Metals, alloys and intermetallics
• MS 5: Carbon-based materials, soft matter and polymers
• MS 6: Nanoparticles, 2D materials, nanocomposites and catalysts
• MS 7: Ceramics, oxides and minerals

eBIC and CCP-EM are proud to announce the inaugural symposium of eBIC, the UK national cryoEM centre at Diamond Light Source, and the third CCP-EM Spring Symposium. This three day conference will be held at the Diamond/RAL Campus, Harwell, Oxfordshire.

The eBIC opening symposium will be on the first day, highlighting the advances of cryoEM and feature presentations with an emphasis on emerging and challenging technologies, followed by CCP-EM Spring Symposium featuring of state-of-the-art presentations related to cryo-EM methods and applications. Confirmed speakers include:

eBIC Speakers

Yifan Cheng, UCSF School of Medicine
John Briggs, MRC Laboratory of Molecular Biology
Lori Passmore, MRC Laboratory of Molecular Biology
Radostin Danev Max Planck Institute of Biochemistry
Greg McMullan, MRC Laboratory of Molecular Biology
Sharon Wolf, Weizmann Institute of Science

CCP-EM Speakers

Piet Gros, Utrecht University
Maya Topf, Birkbeck / UCL
David Waterman, STFC
Tanmay Bharat, MRC Laboratory of Molecular Biology / University of Oxford
Paul Adams, Lawrence Berkeley National Laboratory
Tristan Croll, University of Cambridge
Erik Lindahl, SciLifeLab
Kay Grunewald, STRUBI
Carolyn Moores, Birkbeck / UCL
Morgan Beeby, Imperial College London
Rob Nicholls, MRC Laboratory of Molecular Biology
Ausra Domanska, University of Helsinki
Becky Thompson, University of Leeds

Places are limited and registration will be on a first come first serve basis.

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Bridging the gap between cryo-EM and crystallography

AICS2017 "Bridging the gap between cryo-EM and crystallography" will offer
the opportunity to young researchers in biochemistry or structural biology
at the PhD/postdoctoral level to approach the fundamental questions arising
from the cryo-EM experiment setup. Central topics will include evaluation of
sample suitability for analysis and its preparation, choice of appropriate
instrumentation for single particle, tomography or electron diffraction
approaches, data processing and interpretation of results. A showcase of
recent results will contour the tutorial sessions.

Deadline for registration: 15 June 2017

The meeting is organized by the Sealy Center for Structural Biology & Molecular Biophysics
and co-sponsored by the Keck Center for Computational & Structural Biology

This year's speakers include:

James Chou, Ph.D., Harvard Medical School
Rachelle Gaudet, Ph.D., Harvard University
Petr Leiman, Ph.D., Univ. of Texas Medical Branch
Daniela Nicastro, Ph.D., Univ. of Texas Southwestern Medical Center
Brian Shoichet, Ph.D., Univ. California San Francisco School of Pharmacy
Kylie Walters, Ph.D., Center for Cancer Research, National Cancer Institute

Topics will include:

• Qualitative Phase Analysis with XRPD
• Quantitative Phase Analysis: Single-peak, Whole-Pattern Methods and Beyond
• Amorphous, Mesomorphous and Nano Materials
• Non-Ambient Powder X-ray Diffraction
• New Developments/Complementary Techniques
• Formulation and Product Development
• Polymorph, Salt and Co-crystal Screening
• Crystal Structure Prediction, Elucidation and Verification from Powder Diffraction Data

Keynote:Â Dr Petra Fromme X-ray free electron lasers (XFELs)

To be held at Advanced Photon Source, Argonne National Laboratory.

The school comprises:
Data collection workshop: beamline training; data collection on GM/CA@APS beamlines 23ID-D and 23ID-B equipped with Pilatus3 6M and Eiger 16M detectors, respectively; and data processing. For data collection, only the participants' crystals will be used.
Crystallographic computation workshop: will feature many modern crystallographic software packages taught by authors and other experts. The daily schedule will be organized in three sections â€" lectures, tutorials, and hands-on, interactive trouble-shooting of the technical difficulties the participants face in their projects. We have had considerable success resolving these problems in past years, attested by resulting publications

Applicants: Graduate students, postdoctoral researchers and young scientists at the assistant professor level, along with commercial/industrial researchers are encouraged to apply. Only 20 applicants will be selected for participation. Participants of the workshop are strongly encouraged to bring their own problem data sets or crystals so the problems can be addressed during data collection and/or computation workshops.

Application: Application deadline is April 19. For the application form, the program, contact info and other details click here.

Registration fees: The registration for application is free but there is $500 participation fee for the selected academic students and $950 for the industrial researchers. The link for the on-line payments and instructions will be provided once the selection process is completed. The students will be responsible for their transportation, lodging and breakfast. The workshop organizers can assist in making the reservations at economical lodging at the Argonne Guest House. The workshop will cover all other expenses.

The Residential School on Medicinal Chemistry and Biology in Drug Discovery is designed for chemists and biologists interested in broadening their understanding of the fundamental principles of drug discovery research and preclinical development. Scientists from related disciplines would also gain a clearer appreciation for the processes and methods important to drug discovery through clinical development.

UXSS is an annual event jointly organized by the Center for
Free-Electron Laser Science (CFEL) at DESY and the PULSE institute at
SLAC National Accelerator Laboratory. As you can see from the list of
speakers below, the program will be highly interdisciplinary, with
topics ranging from accelerator physics to molecular biology. There
will also be a coursework exercise involving a mock proposal for the
European XFEL, with the help of experienced mentors.

Registration will open on the 31st January 2017. Please
note that the number of summer school participants will be limited. In
order to facilitate the selection of participants, we ask applicants to
provide a short description of their educational and scientific
background and their motivation for applying for participation in UXSS
2017. The registration deadline will be the 31 March 2017.

Financial support for UXSS 2017 is very kindly provided by the Joachim
Herz Stiftung, meaning that participants will be asked to pay a
registration fee of only 100 EUR. Accepted applicants will receive
a financial contribution towards travel and accommodation expenses.

List of lecturers:
Rasmus Ischebeck (PSI), FEL diagnostics
Hae Ja Lee (SLAC), matter in extreme conditions
Filipe Maia (Uppsala University), coherent diffractive imaging
Giorgio Margaritondo (EPFL), fundamentals of X-ray sources
Arwen Pearson (CUI & University of Hamburg), structural biology
Robin Santra (DESY, University of Hamburg), X-ray - matter interactions
Joachim Stohr (SLAC, Stanford University), condensed matter and magnetism
Simone Techert (DESY & Göttingen Campus), structural dynamics
Linda Young (Argonne/UChicago), atomic and molecular physics

The BBS has organised a range of events across the UK to support this initiative and help raise awareness of our discipline.

Biochemistry Department Lecture with speaker Achillefs Kapanidis, University of Oxford, UK.

Hosted by the Graduate Student Society (Oxford University Biochemical Society) and supported and sponsored by the British Biophysical Society. When: March 7, 13:00-14:00 Where: Biochemistry Building, Main Seminar Room, off South Parks Road OX1 3QU http://www.bioch.ox.ac.uk/aspsite/index.asp?sectionid=seminars

Special edition seminar for the "Molecular Microbiology" seminar series.

When: March 7, 13:00 Where: University of East Anglia, UK: Prof Steve Meech, School of Chemistry, UAE, will give a lecture entitled: "Mechanism of Operation of Blue Light Sensing Flavoproteins â€" From 100 Femtoseconds to 10 microseconds

Oxford Chemical Biology Meeting on and for “Biophysics Week”

Sergi Garcia-Manyes (King's College, Physics, London) with a talk entitled: "Linking mechanochemistry to protein folding at the single bond level" and Ramin Golestanian (Oxford Physics) with a talk entitled: "Self-organization due to catalytic activity” hosted by Hagen Bayley. Where: University of Oxford, Chemistry Department When: Monday 7th, 18:00 - 19:00

Department of Chemistry, Cambridge University

Dr David Klenerman, FRS, will give a lecture on "New insights into neurodegenerative disease from single molecule studies of protein aggregates". Hosts: Alan Fersht, FRS & Richard Henderson, FRS. When: Tuesday 8th March 16:15 Where: Max Perutz Lecture Theatre, Laboratory of Molecular Biophysics, Cambridge.

University of York: The Biological Physical Sciences Institute (BPSI)

will host a talk entitled: "Discrimination of human mesenchymal stromal cell lines using Raman spectroscopy” by: Raquel De Almeida Rocha Ponzoni, Dept of Physics University of York and Physics Lecturer and Universidade Tecnológica Federal do Paraná, Campus Dois Vizinhos - Brazil, When: March 9, 16:00 Where: Wentworth College

Research Complex, Harwell: A mini-symposium to celebrate “Biophysics Week”, will be held at RC@H

Details and registration at: https://www.eventbrite.co.uk/e/a-mini-symposia-on-biophysics-tickets-21522744107

The eighth edition of the Macromolecular Crystallography School is to be held at the Institute Química-Física Rocasolano - CSIC (Madrid).

 Invited speakers and tutors:

• Paul Adams, Berkeley, USA
• Pavel Afonine, Berkeley, USA
• Armando Albert, Madrid, Spain
• Roeland Boer, Barcelona, Spain
• Jose M Carazo, Madrid, Spain
• Kay Diederichs, Konstanz, Germany
• Paul Emsley, Cambridge, UK
• Rafael Fernández-Leiro, Cambridge, UK
• Carmelo Giacovazzo, Bari, Italy
• Xavier Gomis-Ruth, Barcelona, Spain
• Juan A. Hermoso, Madrid, Spain
• Eugene Krissinel, Oxford, UK
• José Martín-García, Arizona, USA
• Rob Nicholls, Cambridge, UK
• Maria Solá, Barcelona, Spain
• Isabel Usón, Barcelona, Spain
  

The workshop has been designed for postgraduate, postdoctoral and research scientists that deal with macromolecular crystallography but need further knowledge on the routine uses, the state of the art and fundamentals that underlie the modern techniques for macromolecular crystallography. The topics will cover crystallographic computing and fundamentals using XDS, CCP4 and Phenix, as well as the state of the art on topics such as the strategies for protein production, data collection,phasing and refinement with ARCIMBOLDO, SHELX and SIR2014 and modeling with COOT.

This year a full-day on breakthrough techniques such as XFEL and cryo EM has been introduced.

MCS2017 will provide six days of lectures and workshops. The course is designed for 25 highly motivated attendants.

Requests to participate must be sent by a free-formated E-mail, before March 10, 2017 to the following address: [email protected], indicating the motivation to participate and experience on macromolecular crystallography and including a letter of recommendation from PhD Director (only for PhD students).

Accepted participants will be notified by e-mail before March 17, 2017.

Organizers: Armando Albert ([email protected]), Juan A. Hermoso
([email protected]) and Isabel Usón ( [email protected]).

Developing the Synergy between Biophysics and Medicinal Chemistry to Deliver Better Drugs

This new edition will cover current hot topics including integral membrane proteins (Special Focus of the Conference).

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