The European Powder Diffraction Conference, EPDIC, is a biannual conference dedicated to all aspects of the analysis of polycrystalline materials by diffraction methods. Each EPDIC has the aim to highlight the latest developments in powder diffraction including methodology, data analysis and instrumental advances. EPDICs traditionally bring together scientists from institutes, universities and instrumentation companies to discuss the progress in academic and industrial research related to powder diffraction. The 17th edition of EPDIC (EPDIC17) will take place in the town of Šibenik, an emerging star of the Croatian Adriatic coast.

The main objective of this workshop is to offer a theoretical and practical training in the different techniques used in integrative structural biology (X-ray diffraction, small angle X-ray scattering, NMR, cryo-electron microscopy, sample preparation for structural biology, biophysical methods to study and characterize macromolecular interactions). The goals are to explain and illustrate, to an audience mainly composed of doctoral students and young researchers, the contributions and limitations of each method with a strong emphasis on their complementarity and future developments.

Registration is now open at:Â https://ecolebios2019.sciencesconf.org/Â

Registration deadline: 22nd April 2019Â

The official language of the workshop is French but presentations may be given in English, depending on the overall profile of the students. For practicals, English and French speaking groups may be organised.

Structural Biology: Deeper into the Cell

• Cryo-EM
• Small molecule structure-based design
• Fragment-based screening
• Biologics and protein engineering
• Emerging technologies
• Membrane proteins
• NMR spectroscopy
• Biophysics
• X-ray crystallography

RapiData is a practical course in macromolecular X-ray diffraction data collection, data processing and structure solution. The aim of the RapiData course is to educate and train young scientists in data collection and processing methods at synchrotron beamlines, using state-of-the-art software and instrumentation. The course will be held at the Stanford Synchrotron Radiation Lightsource (SSRL) located on the SLAC National Accelerator Laboratory campus in Menlo Park, CA, from May 5-10 2019. Course organizers for 2019 are Silvia Russi, Clyde Smith and Jeney Wierman.

Please visit http://smb.slac.stanford.edu/news/rapidata/rapidata-2019/ and use the links on the "registration" page to apply for the course. The application deadline is December 31 2018 Successful applicants will be notified early in January 2019 and invited to register and book accommodation at the SLAC Guesthouse at that time. A limited amount of travel support funding may be available.

• Structure from Single Particles, Fibrils, and Nanocrystals
• New Visionary Methods in SPI and Nanocrystal Imaging
• Time-Resolved Serial Femtosecond Crystallography
• Serial Synchotron Crystallography and CryoEM
• Serial Crystallography Data Analysis Developments
• Serial Crystallography Instrumental Developments

2019 marks a special milestone for CCP4 as it is will be 40 years since the project was set up, we hope you will join us in Nottingham to celebrate the occasion. The meeting will include a Molecular Replacement clinic session where help and advice on delegates MR problems will be available from MR program and pipeline developers.

 Key Dates:

• Â Early bird registration final date: 18 November 2018;
• Â Standard Student bursaries are open to all students registering during early bird period i.e. now until 18 November which cover the cost of registration plus one night accommodation in halls;
•  Travel bursaries are available for students and young postdocs studying at overseas labs to help cover cost of travel to UK. The deadline for applications is 31 October 2018;
• Â Registration closes 10 December 2018.

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The symposium focuses on cutting-edge research in the fields of macromolecular crystallography, Cryo-EM, small angle scattering, electron diffraction, mass-spectroscopy, NMR, molecular dynamics and use of XFELs, and how these and other experimental approaches can be efficiently combined to resolve structure/function relationships in life science and medicine. The target group is academic researchers as well as researchers from large-scale facilities, health care and industry.

The program is centered around invited internationally leading keynote speakers and shorter invited talks as well as Clip-session presentations and round table discussions, and will be an excellent platform for national and international networking. *Both experienced specialists and researchers with more recently established interests in integrative structural biology are expected to greatly benefit from the symposium*.

Programme Overview

• Sunday 2nd December: Registration and introductory talks and student poster session
• Monday 3rd December: Preparations for beamtime and data collection at beamline Â
• Tuesday 4th December: Data processing theory and data processingÂ
• Wednesday 5th December:Â Experimental phasing talks and tutorialsÂ
• Thursday 6th December: Experimental phasing talks and tutorials
• Friday 7th December: Molecular replacement talks and tutorials
• Saturday 8th December:Â Model building and refinement talks and tutorials
• Sunday 9th December: Model validation, Q&A, followed by the workshop dinner
  

The closing date is 7th October.

Organized at Utrecht University together with Thermo Fisher Scientific

• The Integrative Structural Biology Autumn School aims to create an
  opportunity to learn about the synergies between electron microscopy, mass
  spectrometry and modelling in structural biology, next to hands-on
  experience with cross-linking and integrative modelling.
  
• Learn how screening of your samples by native mass spectrometry
  can help accelerate the time to obtain 3D structures or how integrative
  modelling can increase the fidelity of your structure.
  
• Benefit from experts and take home the hands-on experience and
  best practices for cross-linking and integrative modelling.
  
• Take the chance to network with other structural biologists
  across international borders.
• Stay up-to-date on latest Thermo Scientific instrument
  developments and methods.

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• High accuracy models - Randy Read (Cambridge University, UK)
• Model topology - Matteo Dal Peraro (EPFL, Lausanne, Switzerland)
• Contact prediction - Andras Fiser (Albert Einstein College of Medicine, New York, NY, USA)
• Model refinement - Randy Read (Cambridge University, UK)
• Assembly (quaternary structure and complexes) - Jose Duarte (RCSB, San Diego, CA, USA)
• Model accuracy estimation - Chaok Seok (Seoul National University, South Korea)
• Data assisted models - Gaetano Montelione (Rutgers, USA), Susan Tsutakawa /Greg Hura (LBL, Berkeley, CA, USA), and Andras Fiser (Albert Einstein College of Medicine, New York, USA)Â
• Biological relevance of models ? Rosalba Lepore (University of Basel, Switzerland)

• David Koes (U Pittsburgh), is a pioneer in the application of convolutional neural networks to molecular docking
• Wah Chiu (Stanford), is a leader in cryo-electron microscopy.

- d’exploiter les structures tridimensionnelles avec un bon sens critique,

- de résoudre la structure tridimensionnelle d’une macromolécule par cristallographie.

Topics of interest include (but are not limited to):

• Membrane biophysics, including adhesion, signalling and transport phenomena
• Artificial membranes for bottom-up synthetic biology and nanomedicine
• Equilibrium and out-of-equilibrium effects in nanostructured soft interfaces
• Interfacial DNA nanotechnology
• Advanced emulsification and compartmentalisation techniques

The registration for the 3rd Annual Conference of NEUBIAS in Luxembourg City, 2 - 8 February 2019 is now open.

The 3rd Annual Conference of NEUBIAS, gathering the whole BioImage Analysis Community into a multi-faceted event, offers two parallel Training Schools for selected early career and advanced analysts and a Working Meeting (Taggathon) for invited taggers, which precede a Large Symposium dedicated to recent Scientific Developments and Open Tools in BioImage Analysis. Participation in the Symposium is open to all from academia and industry, where participants will be accepted until all spots are filled.

Topics of the Symposium

• BioImage Analysis in Life Science
• Current Developments
• Applications
• Machine Learning
• BioImage Data Mining
• Data Storage

NEUBIAS Highlights

• Image Analysis Satellite Meeting
• Open Source Software Lounge
• Call4Help Session
• Industry Workshops
• Industry TechBites and Digital Posters
• Panel Discussion and more

Biomolecular topics include:

X-ray Crystallography
Cryo-EM
X-ray tomography
Cryo -ET
X-ray free electron lasers

Please submit abstracts to [email protected] (Deadline September 14, 2018)

Conference Registration (Deadline August 27, 2018)

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This workshop will cover data collection, processing and structure solution. Details are available at http://www.ccp4.ac.uk/schools/Japan-2018 , with more to follow. Registration is on the same site.

Registration will close on 24 August.

Topics will include XDS (Kay Diederichs), DIALS (Graeme Winter), the CCP4 suite (Charles Ballard and others), PDB_REDO (Robbie Joosten), COOT and others. The format will cover data collection, lectures, tutorials and problem solving, so students are encourages to bring their own data to work on.