DENSS

Entered: Wed Feb 15 2023

Operating systems: Linux; MacOS; Solaris; SunOS; Unix; MS Windows; Web services

Type: Source

Languages: Python

Distribution: Free GPLv3

Application fields: Biology; Characterization; Data analysis; Modelling; Scattering; Structure

Bibliography: Grant, T.D. (2018) Nature Methods. 15, 191–193.

Description: DENSS is an algorithm that reconstructs the 3D density of a molecule from the 1D solution scattering (SAXS) profile using a novel iterative phase retrieval procedure. DENSS takes as input the 1D scattering data and outputs a standard MRC formatted density map. Several tools and scripts are included for performing data analysis, calculation of the pair distribution function and particle size estimates, averaging of multiple MRC maps, and alignment of PDB atomic models to density maps. An online web server called DENSSWeb is also available at denss.ccr.buffalo.edu.

References: https://github.com/tdgrant1/denss