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Acta Cryst. A clocks up 1.25 millionth structure for the CSD
![[Thumbnail]](https://www.iucr.org/__data/assets/image/0019/158014/ibuprofen.png "Thumbnail")
In 2019, the Cambridge Structural Database (CSD) reached 1 million structures, leading the way in structural data to inform drug discovery and materials development. Since then, the wealth of information available through the CSD has continued to grow, and in August 2023 the Cambridge Crystallographic Data Centre (CCDC) announced that the CSD had passed the milestone of 1.25 million expert-curated experimental crystal structures. We are delighted to announce that this achievement was reached with the electron diffraction structure of ibuprofen published in Acta Crystallographica Section A: Foundations and Advances by Malak Khouchen, Paul Klar, Hrushikesh Chintakindi, Ashwin Suresh and Lukáš Palatinus (CSD Entry: JEKNOC16). This work examines various models for the correction of estimated errors of reflection intensities in electron diffraction data, proving how one of those could notably enhance the accuracy of atomic positions and covalent bond lengths, and improve R factors.
In response to achieving the 1.25 millionth structure, Dr Palatinus commented,
“It is an unexpected privilege and pleasure to have helped to achieve such an important milestone for the CSD and for the whole crystallographic community.
I always illustrate the importance of crystallography to my students by reminding them that the number of published structures grows with the pace of about one structure every 10 minutes, day and night, 24/7. 1.25 million published structures is an amazing number, and I want to congratulate the whole team behind the CSD as well as to all fellow crystallographers who made this possible.
I think it is also symptomatic that the 1.25 millionth CSD structure is a structure determined by 3D electron diffraction. I believe that the number of structures determined by 3D ED in the CSD will quickly grow in the near future.”
The number of structures in the CSD measured using electron diffraction techniques is increasing rapidly. Today the CSD contains over 300 electron diffraction structures.
This article has been adapted from a CCDC blog by Giada Truccolo with permission.
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