Diffraction Data Collection

A Research Resource for Protein Crystallography has been set up at the U. of California, San Diego (UCSD, USA). This Resource has a high-speed data collection system (Mark III) using a rotating anode X-ray source and two multi-wire area detectors. It can routinely collect data for protein crystals with unit cell dimensions up to 220 Å. The Mark II and Mark III systems can be used free of charge by any protein or small molecule crystallography group. To apply for machine time, please send a one-page proposal to Prof. N.-H. Xuong, Dept. of Physics, 0319, UCSD, La Jolla, CA 92093-0319. The proposals will be examined by an Advisory Committee which will assign priorities on the basis of feasibility and scientific merit. Proposals should include the following: (1) aim (including why you need the facility); (2) significance; (3) space group and unit cell dimensions; (4) quality of the diffraction pattern; (5) heavy atom derivatives; (6) whether or not a cooling device is needed, and if so, what temperature; and (7) name, address, and telephone number.