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High-speed data collection time available

A Research Resource for Protein Crystallography has been set up at University of California at San Diego (UCSD). This resource has a high-speed data  collection system (Mark III) using a rotating anode X-ray source and two multiwire area detectors. It can routinely collect data for protein crystals with unit cell dimensions up to 220 Å. With a crystal of decent diffracting power, the data rate will be between 50,000 and 150,000 intensity measurements per day, with Rsym in the range of 5% to 7%. An image plate detector mounted on a molybdenum X-ray beam (λ = 0.71 Å) that can be used to collect data at very high resolution (0.8 to 1.2 Å) for small protein crystals will also be available. It can be used effectively for small molecule crystals with a data collection rate about 10 times faster than a standard diffractometer. The Mark II and Mark III systems can be used free of charge by any protein or small molecule crystallography group. To apply for machine time, please send a short proposal (about one page) to Nguyen-huu Xuong, Dept. of Physics, 0319, U. of California at San Diego, La Jolla, California 92093-0319, USA. The proposals will be examined by an Advisory Committee which will assign priorities on the basis of feasibility and scientific merit.

The Advisory Committee meets in August and January. Proposals should be received by the 15th of the month preceding review.

Nguyen-huu Xuong